Laminin’s essential role in cell differentiation, migration and adhesion can now be found in a stable, easy-to-use bioink.
GelXA-LN111 has been developed as a bioink for application with cells that require the presence of the laminin 111 isoform. Laminin 111 is important during early development of the lining of tissues and organs. Specialized applications that this bioink is suited for include the culture of brain, kidney, liver or intestinal cells. In disease modeling, this bioink is relevant for studying Parkinson’s disease and cancer models.
GelXA-LN121 has been developed as a bioink for application with cells that require the presence of the laminin 121 isoform. Laminin 121 is widely expressed during embryonic and early development of the lining of tissues and organs. This laminin variation is also
found predominantly in the placenta, skeletal muscle, and kidney tissue. Laminink 121 is particularly suitable as a base material for the culture of several cell types, including skeletal muscle, brain, kidney and liver cells.
GelXA-LN411 has been developed as a bioink for application with cells that require the presence of the laminin 411 isoform. Laminin 411 supports many different tissue types including cells from the pancreas, vascular, immune, nervous, hematopoietic systems. This bioink is suitable as a base material for the culture of several specific cell types, including pancreatic cells and neurons.
GelXA-LN521 has been developed as a bioink that supports cells that requiring laminin 521 and therefore Laminink 521 induces self-renewal of these cells. In addition, Laminink 521 supports many diverse tissue cell types, such as cells from pancreas, vascular, nervous and muscular systems. Furthermore, the bioink can be used as a base for many specialized cells including hepatocytes, cardiomyocytes, and neurons.
GelXA-LN+ is a blend of several types of laminins. This bioink retains the excellent printability and ease of crosslinking found with the universal CELLINK® bioink. Laminink+ can be used as a great starting point for the culture of many cell types. Our revolutionary blend of laminins within this bioink has been optimized to maximize cell viability.
All these incredible new bioinks can be printed at room temperature and offer dual crosslinking capabilities via UV exposure or treatment with ionic crosslinking agent.