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GelX Series

GelXG and GelXA build on the great success that our collaborators and customers have had with CELLINK GelMA. Despite the representative environment that GelMA provides, we understand it can be difficult to print with due to thermosensitivity. CELLINK GelXA and CELLINK GelXG are two new blends that can be printed at room temperature. We improved the printability, ease of use, and stability of GelMA by blending it with Xanthan Gum (GelXG) and alginate (GelXA).

This base material allows the user to choose between using photoinitiator assisted or ionic crosslinking, or the combination.

Printability data

  • 22G
  • 25G
  • 27 G

Conical tip (Room temperature)
This diagram displays the printability behaviour and characteristics of GelXA, when being printed with a 22G conical tip at room temperature (approx. 23.4 °C) at 30-40 kPa.

22G

Lines
In order to assess printability one has to consider a lot of factors. Here we can see how GelXA performs when printing straight lines, using a printing pressure of 22 kPa.

GelXA 22G

Conical tip (Room temperature)
This diagram displays the printability behaviour and characteristics of GelXA, when being printed with a 25G conical tip at room temperature (approx. 23.4 °C) at 30-40 kPa.

25G

Lines
In order to assess printability one has to consider a lot of factors. Here we can see how GelXA performs when printing straight lines, using a printing pressure of 25 kPa.

GelXA 25G

Conical tip (Room temperature)
This diagram displays the printability behaviour and characteristics of GelXA, when being printed with a 27G conical tip at room temperature (approx. 23.4 °C) at 30-40 kPa.

27 G

Lines
In order to assess printability one has to consider a lot of factors. Here we can see how GelXA performs when printing straight lines, using a printing pressure of 27 kPa.

GelXA 27G

22G

Conical tip (Room temperature)
This diagram displays the printability behaviour and characteristics of GelXA, when being printed with a 22G conical tip at room temperature (approx. 23.4 °C) at 30-40 kPa.

22G

Lines
In order to assess printability one has to consider a lot of factors. Here we can see how GelXA performs when printing straight lines, using a printing pressure of 22 kPa.

GelXA 22G

25G

Conical tip (Room temperature)
This diagram displays the printability behaviour and characteristics of GelXA, when being printed with a 25G conical tip at room temperature (approx. 23.4 °C) at 30-40 kPa.

25G

Lines
In order to assess printability one has to consider a lot of factors. Here we can see how GelXA performs when printing straight lines, using a printing pressure of 25 kPa.

GelXA 25G

27 G

Conical tip (Room temperature)
This diagram displays the printability behaviour and characteristics of GelXA, when being printed with a 27G conical tip at room temperature (approx. 23.4 °C) at 30-40 kPa.

27 G

Lines
In order to assess printability one has to consider a lot of factors. Here we can see how GelXA performs when printing straight lines, using a printing pressure of 27 kPa.

GelXA 27G

Customizations

GelXG
CELLINK GelXG is a gelatin-based bioink blended with Xanthan Gum. This exciting addition provides an environment with similar properties to that of native mammalian cells, but with improved printability and stability.

GelXA-Bone
Developed for studying targeted cell differentiation. This bioink is well-suited for use as a base material in bone constructs or thermopolymer supplement constructs.

GelXA-Fibrin
For studying wound-healing environments,  contains in situ fibrin and fibrinogen for the formation of complex, stable networks.

GelXA-SKIN
Provides the printability and versatility of GelXA with in situ fibrin and fibrinogen to better represent the native environment of skin cells.

GelXA- LAMININK
Laminin’s essential role in cell differentiation, migration and adhesion can now be found in a stable, easy-to-use bioink.

GelXA-LN111 has been developed as a bioink for application with cells that require the presence of the Laminin 111 isoform. LAMININ 111 is important during early development of the lining of tissues and organs. Specialized applications that this bioink is suited for include the culture of brain, kidney, liver or intestinal cells. In disease modeling, this bioink is relevant for studying Parkinson’s disease and cancer models.

GelXA-LN121 has been developed as a bioink for application with cells that require the presence of the Laminin 121 isoform. LAMININ 121 is widely expressed during embryonic and early development of the lining of tissues and organs. This laminin variation is also
found predominantly in the placenta, skeletal muscle, and kidney tissue. LAMININK 121 is particularly suitable as a base material for the culture of several cell types, including skeletal muscle, brain, kidney and liver cells.

GelXA-LN411 has been developed as a bioink for application with cells that require the presence of the Laminin 411 isoform. LAMININ 411 supports many different tissue types including cells from the pancreas, vascular, immune, nervous, hematopoietic systems. This bioink is suitable as a base material for the culture of several specific cell types, including pancreatic cells and neurons.

GelXA-LN521 has been developed as a bioink that supports cells that requiring Laminin 521 and therefore LAMININK 521 induces self-renewal of these cells. In addition, LAMININK 521 supports many diverse tissue cell types, such as cells from pancreas, vascular, nervous and muscular systems. Furthermore, the bioink can be used as a base for many specialized cells including hepatocytes, cardiomyocytes, and neurons.

GelXA-LN+ is a blend of several types of laminins. This bioink retains the excellent printability and ease of crosslinking found with the universal CELLINK® bioink. LAMININK+ can be used as a great starting point for the culture of many cell types. Our revolutionary blend of laminins within this bioink has been optimized to maximize cell viability.


All these incredible new bioinks can be printed at room temperature and offer dual crosslinking capabilities via UV exposure or treatment with ionic crosslinking agent.