GelMA Series Story

At CELLINK we aim to provide the most consistent and highest quality GelMA on the world market.

Gelatin methacrylate (GelMA) has become one of the cornerstone bioinks in the bioprinting field due to its extraordinary flexibility in applications. GelMA is a photocrosslinkable version of gelatin whose amine groups have been partially replaced with methacrylate groups. Our GelMA is produced in the heart of America with the finest raw materials. The GelMA is made by scientists, for scientists with a process that has been refined and optimized. Extensive quality control is performed on every batch to ensure reproducibility and consistency.

Thorough Quality Control

To ensure that each bioink supports cellular life, we use sterile and aseptic production conditions and test all raw materials for endotoxin levels and sterility. We also verify the appearance, pH and cytotoxicity of the final product for every batch of bioink we produce. We understand the importance of consistency in research. To ensure reproducibility, we verify each bioink’s viscosity, critical gel point and degree of methacrylation. Controlling each of these properties is critical as they can all affect your results.

The quality control of our bioinks starts with its printability and rheological properties. The GelMA Series is optimized for bioprinting near the gel point as their viscosity decreases steadily as the temperature rises. With our GelMA, you can print a continuous filament with a diameter below 1 mm.
We verify that each bioink is shear thinning at given conditions to ensure your bioprinting is smooth and reproducible. GelMA-based bioinks only demonstrate shear thinning at shear rates above 0.1 s-1 due to their amorphous nature and the force needed to begin flow.
Bioprinted GelMA is easily crosslinked via photopolymerization of methacrylic functional groups, initiated by the photoinitiator LAP. It takes only 5 sec to obtain a mechanically stable constructs, though even higher stiffness can be achieved by increasing the photocrosslinking time.

Customizations

GelMA A

GelMA A is a result of a unique blend of GelMA and alginate, which provides the most advantageous gelatin-based bioink in the world. This blend exhibits unparalleled printability at room temperature with a minimal risk for nozzle clogging, even in bioprinting systems with no thermal control. Crosslinking is possible through either light activation of the photoinitiator or through the addition of our ionic crosslinking solution, which allows tuning the mechanical properties of printed constructs for the best match with desired engineered tissues.

GelMA C

GelMA C is a special blend of GelMA and nanofibrillar cellulose, which takes advantage of the best features of both components. This blend exhibits smooth printability at room temperature without a thermal control, and also provides fibrillar morphology benefiting certain cell types. GelMA C is quickly crosslinked through light activation of a photoinitiator or through the addition of our ionic crosslinking solution. The ink retains its shear thinning properties at physiological conditions exhibiting excellent printability through a wide range of nozzle diameters and at low extrusion pressures.

GelMA HA

The GelMA HA has been formulated to incorporate methacrylate hyaluronic acid into our globally known GelMA products. Hyaluronic acid plays an important role in a wide variety of different tissues such as skin, cartilage, bone, and nerves. The research possibilities are immense.

GelMA HIGH

Our GelMA is now available in syringes as a ready-to-use reconstituted formulation at physiological pH and osmolarity without a photoinitiator. Quickly tailor your own GelMA bioink or 3D cell culture composition by simply diluting our high concentration buffered GelMA solution with a photoinitiator or other additives. Warm it up, mix well, and deliver results. GelMA preparation has never been quicker.

Bio Conductink

This bioink is deliberately designed for studies of muscular contraction and nerve repair. Bio Conductink creates an electrically conductive cell environment for neural and muscle cells that enables their communication and network formation. We designed it to provide users with excellent printability and very low cytotoxicity. Make your cells communicate now.