A series

Simple and powerful

The A Series bioinks are composed of high-quality raw alginate materials to enable high reproducibility in your research. Alginate is an FDA-approved, naturally derived polysaccharide isolated from the cell walls of brown algae. Due to its versatility, it is used in many applications ranging from food to drug delivery studies.

Alginate’s biocompatibility and ease of use make it a useful material in tissue engineering applications, including bone and cartilage. Alginate can be modified to contain nearly any peptide sequence, enabling users to fabricate cell-specific biomaterials to guide cell differentiation and tissue formation. Our CELLINK A-RGD bioink is designed to leverage this property.

Alginate dissolved in mannitol solution ensures an excellent environment with the correct osmotic pressure for mammalian cells. Due to its translucent appearance, alginate minimizes optical interference when making both brightfield and fluorescent images. This enables imaging of several layers of cells in a 3D construct.

The product series:

CELLINK A

CELLINK A is a viscous alginate hydrogel, suitable for both bioprinting and casting. Its simplicity is also its strength; you can use it on its own, mix it with another hydrogel to make the blend crosslinkable with calcium ions or prepare an encapsulation of a cell-laden bioink. These are just a few potential applications — let your imagination run free!

CELLINK A-RGD

CELLINK A-RGD consists of alginate covalently conjugated with the L-Arginine-Glycine-L-Aspartic Acid peptide sequence covalently conjugated, also known as RGD. RGD improves cell attachment and has wide applicability in engineering nearly every tissue. The sequence has also been used for surfacing implants including bone and vascular implants to improve integration within the body.