Laminins are proteins composed of three subunits — α-chain, β-chain and γ-chain. They are a major component of the basal lamina lining a cell membrane’s external surface. Its cross-like structure serves as the foundation for many tissues. Laminins play an important role in cell differentiation, migration, adhesion and the support of healthy tissue.
You can use CELLINK LAMININK 121 as the starting point for multiple cell types. Laminin 121 is expressed widely during embryonic and early development stages of organ and tissue lining. This laminin variation is mostly found in placenta, skeletal muscle and kidney tissue. CELLINK LAMININK 121 is particularly suitable as a base material for culturing cell types including skeletal muscle, brain, kidney and liver cells.