What is a bioink?
A bioink is a hydrogel biomaterial that is suitable for bioprinting with mammalian cells and it provides a temporary support to the cells while they produce their own extracellular matrix. Significant advances in 3D bioprinting technology as well as development of new bioinks have made it possible to bioprint complex 3D tissue structures . Bioinks based on biopolymers (e.g. collagen, gelatin, hyaluronan, silk, alginate, and nanocellulose) are known for their favorable biocompatible properties and are attractive biomaterials for cell encapsulation and 3D bioprinting. These bioinks provide an aqueous 3D environment with biologically relevant chemical and physical signals, mimicking the natural extracellular matrix environment.
However, the application of some bioinks for 3D bioprinting of organs with clinically relevant dimensions can be challenging due to their sub-optimal printability . For example, a common challenge when 3D bioprinting alginates is the poor shaped
Even minor deformities, whether is an actual or perceived defect, bring psychological distress upon the affected individuals, especially children. An outer appearance with life-like limbs and tissues is important for their psychological and emotional well-being. For these reasons, tissue engineers, biologists, material scientists, and clinicians have an invested interest and passion to develop a successful clinical therapy for reconstruction through a tissue engineering approach using the patient’s own cells. The innovative methods for engineering human tissues and organs can have a profound effect on the future of medicine. 3D Bioprinting is considered a revolutionizing technology for advancing and accelerating progress in the field of tissue engineering and regenerative medicine. and thus, the future of medicine. We believe we can create this future through a collaborative spirit and by putting our combined expertise to the service of humanity.
The future is created in the present and it belongs to the doers, those that continue moving forward in order to see their vision come to realization. It’s not that we see the future and then move towards it. We move in order to see it.