Living tissues rely heavily on vascular networks to transport nutrients, oxygen and metabolic waste. However, there still remains a need for a simple and efficient approach to engineer vascularized tissue, This has been one of the biggest hurdles to 3D bioprint more complex functional tissues than basic cartilage and, with still limited capacity, skin.

A team of Chinese researchers at University of California at San Diego La Jolla created prevascularized tissues with complex three-dimensional (3D) microarchitectures using a rapid bioprinting method called microscale continuous optical bioprinting (μCOB), a technique which uses light to rapidly cure a bioprinting hydrogel.